Paula K. Shireman, MD, Vascular/Endovascular Surgical Research Laboratory
Director: Paula K. Shireman, MD
Professor of Vascular/Endovascular Surgery
Vice Dean for Clinical and Translational Research
UT School of Medicine San Antonio
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Biosketch
Dr. Shireman is the Principal Investigator on an R01 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health and a Veterans Administration Merit Review grant. Her research focus is on aging and muscle regeneration, collateral artery formation, lower extremity bypass grafts, muscle regeneration and stem cells. Dr. Shireman received her Bachelor of Science in Nutrition from Purdue University in 1986 and her Medical Doctor from Indiana University School of Medicine in 1990. She went on to complete her residency in General Surgery at Northwestern University Medical Center, which included two years of vascular surgery research, in 1997 and a fellowship in Peripheral Vascular Surgery at Loyola University Medical Center in 1999. Dr. Shireman then joined our faculty in the Department of Surgery, is board certified in both General Surgery and Vascular Surgery, and is currently a Professor with Tenure. She also has completed her Master of Science in Clinical Investigation from our Graduate School of Biomedical Sciences in 2004.
Research
Dr. Shireman's lab studies the inflammatory-mediated mechanisms of angiogenesis and skeletal muscle regeneration. We are particularly interested in how hematopoietic stem cells, myogenic stem cells and inflammatory cells interact to form muscle after injury. A better understanding of muscle regeneration will be useful in tissue regeneration strategies for limb salvage.
